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최앵자 ( Choi Ang-Ja ) - 삼성서울병원
최수정 ( Choi Su-Jung ) - 삼성서울병원
최희정 ( Choi Hee-Jung ) - 삼성서울병원
유미영 ( You Mi-Young ) - 삼성서울병원
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Abstract
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Purpose: Continuous renal replacement therapy (CRRT) has become the preferred dialysis method to support critically ill children and neonates with acute kidney injury. Using CRRT on neonates has increased, but reports about experience are limited. The aim of this study is to describe the clinical application, outcomes, and complications of CRRT in children and neonates.
Methods: A retrospective review was performed in 135 children and 36 neonates who underwent CRRT at a tertiary hospital from 2008 to 2015.
Results: At the initiation of CRRT, the median age of children was 72 months and the corrected age of neonates was 37.1 weeks. Median body weight of neonates was 3.2 kg. In neonates, initial degree of fluid overload [FO%], blood flow rate [BFR] and ultrafiltration rate [UFR] rate during CRRT were higher than in children. Median real time of CRRT was 90.5 and 53.5 hours in children and neonates, respectively. Downtime of CRRT was 0.7 and 1.3 hours/day. Median mortality rates (44.4% vs.47.2%) and complication rates were similar between the groups.
Conclusion: CRRT can be used for a wide range of critically ill children and neonates. Different application methods of CRRT can contribute to increased survival of neonates.
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KeyWords
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중증 질환, 소아, 신생아, 신대체요법
Critical illness, Child, Neonate, Renal replacement therapy
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원문 및 링크아웃 정보
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등재저널 정보
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